Hello,
Yes of course, it works. The benefits brought by PCOIP are really important. I'll let you look here a comparative post of PCOIP vs RDP PCoIP vs. RDP | vInfrastructure Blog.
After all depends on what you want to do through the VMs.
Please check somes features here : http://www.vmware.com/files/pdf/view/vmware-horizon-view-best-practices-performance-study.pdf
and here View 5.1 Performance | VMware VROOM! Blog - VMware Blogs
Hope this will help you to understand a little more 
Julien.